I want to connect 4 separate microphones for Ambisonic recording. How do I use four input signals (with separate channels) with adc~ 1, adc~ 2, adc~ 3, adc~ 4?and which is the audio setting, number device , number channel etc..??

set # of channels to 4 in the setup window, and then use a [adc~ 1 2 3 4]. you can use multiple [adc~] but that has all sorts of traps and pitfalls to overcome. What device are you going to be using?

The device that i'm going to use is an external Edirol UA-1000 with 4 inputs microphonic but using [adc~ 1 2 3 4] these inputs are overlapped and they are not separated in Pure Data. For example from the imput one [adc~1] come out the audio signal of mic 1 and 3.

Have a look at the audio IO flags used to start Pd, in particular -audioindev