@federicocogo Ok, now try this:

Applications/Pd-l2ork.app/Contents/Resources/app.nw/bin/pd-l2ork -verbose

See if this is printed to the console:
success reading preferences from...

printed this

Welcome to Pd GUI using Node-Webkit
0.22.1
font stack check: using optimal font sizes.
Pd has started the GUI
canvasinfo: v0.1
stable canvasinfo methods: args dir dirty editmode vis
pdinfo: v.0.1
stable pdinfo methods: dir dsp version
classinfo: v.0.1
stable classinfo methods: size
objectinfo: v.0.1
stable objectinfo methods: class
[import] $Revision: 1.2 $
[import] is still in development, the interface could change!
compiled against Pd-l2ork version 2.3.3 (20171004-rev.fb96e06)
input channels = 2, output channels = 2
working directory is /Volumes/Macintosh HD/Users/federicocogo
input channels = 2, output channels = 2
input device 0, channels 2
output device 1, channels 2
framesperbuf 64, nbufs 13
rate 44100
... opened OK.

@federicocogo What gets printed to the OSX terminal window?

MacBook-Pro-de-Federico:~ federicocogo$ /Applications/Pd-l2ork.app/Contents/Resources/app.nw/bin/pd-l2ork -verbose
Pd-L2Ork version 2.3.3 (20171004-rev.fb96e06)
compiled 22:20:01 Oct 4 2017
port 5400
Trying Wish at "/Applications/Pd-l2ork.app/Contents/Resources/app.nw/../../MacOS/nwjs"
"/Applications/Pd-l2ork.app/Contents/Resources/app.nw/../../MacOS/nwjs" --user-data-dir="/Volumes/Macintosh HD/Users/federicocogo/Library/Application Support/purr-data" "/Applications/Pd-l2ork.app/Contents/Resources/app.nw" 5400 localhost pd-l2ork "/Applications/Pd-l2ork.app/Contents/Resources/app.nw" x100316e30Waiting for connection request...
[1010/182510.626316:WARNING:chrome_main_delegate.cc(565)] final extension: .nw
... connected
Pt_Start() called

@federicocogo Please try out one of the following binaries:

https://git.purrdata.net/jwilkes/purr-data/pipelines/1006

I can't remember whether you are using the 10.8 binary or the default 10.11 one, so both are available.

Anyhow, click the link to the one you are using, then click the button on the next page to download the artifact (which is just a zip file of the dmg).

Let me know if it solves your problem.

Purr Data 10.11 running successfully on osx 10.10.5 yosemite. load preferences correctly.
@jancsika thank you very much for your time and dedication

@federicocogo Great!

I'll put out a bugfix release soon.